The meeting with Donilon drew attention as North Korea is expected to be a key topic.
Park and Donilon met and exchanged greetings and pleasantries before taking the meeting behind closed doors. Further details were not immediately available.
North Korea carried out its third nuclear test on Feb. 12, two months after it successfully launched a long-range rocket. The set of provocations sparked concern that the communist nation could be closer to being capable of launching nuclear-tipped missiles as far as the U.S. mainland.
Seoul and Washington have been in talks over how to punish the North.
Park also held meetings with Canada's Governor General David Johnston, U.N. Deputy Secretary-General Jan Eliasson, Indonesian Vice President Boediono and Peruvian Vice President Marisol Espinoza, as well as a group meeting with representatives of Denmark, France, Britain and Germany.
She was also scheduled to meet with Vietnam Vice President Nguyen Thi Doan, a group of high-level Japanese politicians, Australia's Governor General Quentin Bryce as well as hold group meetings with representatives from Kuwait and Saudi Arabia and with representatives from Afghanistan, Turkmenistan, Gabon, Uzbekistan and Kazakhstan.